Beau knows a thing or two about eating random mushrooms and hoping they'll get you baked, and by 'a thing or two' she means she can reference multiple stories on command (even if she doesn't remember what happened after eating them a couple of times). Sometimes you get desperate and tired and poison yourself a little. It's fine.

That said, of all the people she recognizes at Bonnie's, Jeff seems the absolute most likely to be on drugs at any given point, meaning at first she doesn't clock something's up aside from that when he grabs her and starts muttering.

"Dude, are you having a bad trip or something? You look like you're about to vibrate right outta your skin and not even in a fun way." Yeah, she's trying to get a look at his pupils now even if she knows next to nothing about medical treatment. "If you got something good I'm gonna be so mad if you didn't bring any to share."